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Parsing the role of NSP1 in SARS-CoV-2 infection

ABSTRACT: NSP1 is a major shutoff factor of the SARS-CoV-2 coronavirus, which is responsible for the COVID-19 pandemic. The functions of NSP1 and its contribution to SARS-CoV-2 propagation is not well understood. We tackled these questions utilizing methods such as RNA sequencing, ribosome profiling, and SLAMseq.

ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Mesocricetus auratus Chlorocebus sabaeus Homo sapiens

PROVIDER: GSE200422 | GEO | 2022/04/10

REPOSITORIES: GEO

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Evasion of antiviral innate immunity by SARS-CoV-2 NSP1 is exerted through H3K9 di-methylation

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