Transcriptomics

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RNA-seq of cardiomyocytes exposed to glucose deprivation with or without empagliflozin treatment


ABSTRACT: Glucose-lowering drugs sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of serious heart failure events, regardless of diabetes status, but the underling mechanism of this cardioprotective benefit is unknown. Here, we performed RNA-seq screening in cardiomyocytes to determine the potential cardioprotective mechanism of empagliflozin (EMPA).

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE200598 | GEO | 2022/12/12

REPOSITORIES: GEO

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