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NanoString nCounter NF1-mutant melanoma gene expression

ABSTRACT: Purpose: Digital spatial profiling was used to elucidate the interplay between the tumor cells and the surrounding microenvironment FFPE tissues. Methods: Two tissue microarrays (TMA) were generated from each FFPE block using the ISNET Galileo CK4500 computer-driven tissue microarray. Images of H&E-stained cores were demarcated by a pathologist and were utilized alongside NanoString immunofluorescent staining for morphology markers S100, CD45, CD3, and DAPI to draw region of interest.

ORGANISM(S): Homo sapiens

PROVIDER: GSE200904 | GEO | 2022/04/16

REPOSITORIES: GEO

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