Transcriptomics

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Expression data from livers of 6 and 10-weeks garlic-fed mice


ABSTRACT: Garlic is a popular flavor enhancer in modern cuisines. Although anti-atherosclerotic, anti-proliferative, hypolipidemic and chemopreventative effects of garlic are known for a long time, the mechanisms of garlic as a dietary supplement ramain largely unknown. We used microarrays to analyze the global programme of gene expression in control (cellulose) and garlic-fed C57BL/6J mice serendipitously infected with Pasteurella multocida and identified acute phase response genes, particularly Lcn2 and Orm2, as the major players in the innate response. Also dieraty garlic suppressed pasteurella infection in C57BL/6J mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE20093 | GEO | 2019/12/31

REPOSITORIES: GEO

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