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Gene-expression data of (WT) and knock-out (KO) bone marrow derived macrophages (BMDMs) from C57BL/7 mice

ABSTRACT: We provide gene expression data of wild-type (WT) and various knock-out (KO) bone marrow derived macrophages (BMDMs) from mice (C57BL/6) in different conditions of infections and treatments. We included BMDMs from WT (female and male), Ifnar-/-, IFNg-/-, iNOs-/-, Nlrx1-/- (female and male), Nox2-/- and Prx5-/- mice. BMDMs were either infected with a human protozoan parasite Leishmania guyanensis with or without its endosymbiant double-stranded RNA (dsRNA) virus, Leishmania RNA Virus 1 (LgyLRV1+ and LgyLRV1-, respectively). Alternatively BMDMs were treated with a TLR3 agonist poly I:C, a TLR2 agonist FSL1, with H2O2 or tBHQ.

ORGANISM(S): Mus musculus

PROVIDER: GSE201066 | GEO | 2022/04/20

REPOSITORIES: GEO

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Gene-expression data of female wild-type (WT) and knock-out (KO) bone marrow derived macrophages (BMDMs) from C57BL/7 mice

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