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RNA-seq of non-tumorous liver tissues in LiK and LiKM mice after normal diet or ACR diet

ABSTRACT: KrasG12D mutation and Mdm2 loss in the liver (LiKM) accelerated liver carcinogenesis in mice, compared with LiK (KrasG12D mutation in the liver) mice. Acyclic retinoid (ACR) diet suppressed tumor development in LiKM mice. The goal of RNA-seq of non-tumorous liver tissues is to identifiy the effect of ACR diet on the transcriptomic profile of the liver and clarify the mechamism of ACR-mediated tumor suppression in LiKM mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE201067 | GEO | 2022/08/24

REPOSITORIES: GEO

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