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Copy number variations may contribute to congenital heart defect risk greatly by disrupting long noncoding RNAs

ABSTRACT: We identified lncRNAs locating in CNV locus which were coexpressed with multiple congenital heart defect associated genes. To validate our findings, we performed overexpression and knockdown experiments to characterize the trascriptomic profiles regulated by HSALNG0104472.

ORGANISM(S): Homo sapiens

PROVIDER: GSE201076 | GEO | 2022/04/24

REPOSITORIES: GEO

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Integrated analysis of copy number variation-associated lncRNAs identifies candidates contributing to the etiologies of congenital kidney anomalies.

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