ScRNA-Seq to study the impact of HIV-1 on DC biology [PreDC_Single_Cell_Exp2]
Ontology highlight
ABSTRACT: Pre-DC have been initially described through their ontogeny. Our lab reported for the first time a pre-DC functional specificity in the context of HV-1 capture, infection and in vitro transmission as a consequence of their constitutive expression of Siglec-1. However, pre-DC immune response to viral exposure remained to be studied. This study aim to decipher innate immune response of pre-DC and cDC2 when exposed to HIV-1 in the presence or not of Vpx.
ORGANISM(S): Homo sapiens
PROVIDER: GSE201328 | GEO | 2023/01/13
REPOSITORIES: GEO
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