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Bulk RNA-Seq to study the response of cDC2 and Axl+DC to HIV-1 infection

ABSTRACT: Axl+DC have been initially described through their ontogeny. Our lab reported for the first time an Axl+ DC functional specificity in the context of HV-1 capture, infection and in vitro transmission as a consequence of their constitutive expression of Siglec-1. However, Axl+DC immune responses to viral exposure remained to be studied. This study aim to decipher innate immune response of Axl+DC when exposed to HIV-1 in comparison to other DC subtypes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE189727 | GEO | 2023/01/13

REPOSITORIES: GEO

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