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Human monocyte-derived macrophage response to Aspergillus fumigatus

ABSTRACT: To investigate the influence of Aspergillus fumigatus on iron regulation in macrophages, we obtained macrophages in culture from human derived monocytes and co-cultured the monocyte-derived macrophages with Aspergillus conidia at a 1:1 ratio. We collected samples at 0, 2, 4, 6 and 8 hours and extracted RNA. We then performed gene expression profiling analysis using data obtained from RNA-seq of control macrophages and macrophage co-cultured with Aspergillus fumigatus at five time points.

ORGANISM(S): Homo sapiens

PROVIDER: GSE202286 | GEO | 2022/05/08

REPOSITORIES: GEO

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