Transcriptomics

Dataset Information

0

Transcriptome analysis of hepatocellular carcinoma and adjacent non-tumor liver tissues [I]


ABSTRACT: Integrin alpha 6 (ITGA6) forms integrin receptors with either integrin β1 (ITGB1) or integrin beta 4 (ITGB4). To study its expression and regulatory functions in hepatocellular carcinoma (HCC) progression, whole transcriptome RNA sequencing in paired HCC tumor and adjacent non-tumor liver tissue samples from ten local Hispanic patients was performed. The average expression of ITGA6 was found increased by over 3.5-fold in HCC tumor tissues in comparison with their adjacent non-tumor tissues. The study indicates integrin alpha6-beta4 complex as a potential therapeutic target for treating patients in HCC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE202853 | GEO | 2022/05/18

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-09-25 | GSE233421 | GEO
| PRJNA163077 | ENA
| PRJNA106385 | ENA
2014-11-17 | E-GEOD-61300 | biostudies-arrayexpress
2020-08-07 | PXD011883 | Pride
2019-04-16 | GSE115059 | GEO
2016-08-18 | E-MTAB-4810 | biostudies-arrayexpress
2014-11-17 | GSE61300 | GEO
2017-03-06 | GSE95540 | GEO
2009-01-13 | E-GEOD-11466 | biostudies-arrayexpress