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The Role of Uridine Glucuronosyl transferase 2B28 (UGT2B28) in Prostate Cancer Progression [day30]

ABSTRACT: To understand the effect of UGT2B28 on tumor growth, we generated lentiviral-mediated UGT2B28 knockdown and rescue (by overexpressing UGT2B28 in the knockdown background) in LAPC4 cells. These engineered cells were then subcutaneously injected in athymic nude mice with pre-implanted testosterone pellets. We then performed transcriptomics on the xenograft tumors upon resection at ~30 days

ORGANISM(S): Homo sapiens

PROVIDER: GSE203185 | GEO | 2023/05/13

REPOSITORIES: GEO

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