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RNAseq of tumor endothelial cells isolated from CT2A glioma under control or LGK974 treatment

ABSTRACT: The Wnt signaling pathway regulates blood-brain barrier (BBB) formation and function in both development and pathogenesis of diseases, and is essential for CNS angiogenesis and BBB formation in both embryonic and postnatal development. However, how Wnt signaling affects brain tumor endothelial cells is largely unknown. We isolated endothelial cells from tumors in control or LGK974 treated mice, and analyzed the role of Wnt signaling inhibition on tumor endothelial cells.

ORGANISM(S): Mus

PROVIDER: GSE203374 | GEO | 2023/03/31

REPOSITORIES: GEO

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