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Transcriptome analysis of kidneys of cisplatin-induced AKI model

ABSTRACT: This study was aimed to investigate the role and underlying mechanism of TRPM2 in cisplatin nephrotoxicity. Cisplatin-induced acute kidney injury (AKI) model was established in WT and TRPM2-KO mice. The transcriptome profiling of the kidneys of WT and TRPM2-KO mice treated with cisplatin was compared to find differentially expressed gene which may be related to TRPM2 on cisplatin nephrotoxicity.

ORGANISM(S): Mus musculus

PROVIDER: GSE203584 | GEO | 2023/03/30

REPOSITORIES: GEO

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