Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Kidney
SUBMITTER: Markus Rinschen
LAB HEAD: Thomas Benzing
PROVIDER: PXD005525 | Pride | 2020-01-30
REPOSITORIES: Pride
Items per page: 1 - 5 of 19 |
Kidney international 20181203 2
Acute kidney injury (AKI) leads to significant morbidity and mortality; unfortunately, strategies to prevent or treat AKI are lacking. In recent years, several preconditioning protocols have been shown to be effective in inducing organ protection in rodent models. Here, we characterized two of these interventions-caloric restriction and hypoxic preconditioning-in a mouse model of cisplatin-induced AKI and investigated the underlying mechanisms by acquisition of multi-layered omic data (transcrip ...[more]