Transcriptomics

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Comparing the Transcriptomes of WT oocytes with Lsm14b KO oocytes by RNA-Seq Analysis


ABSTRACT: The success of human reproduction relies on high quality oocytes. Oocyte quality is manifested by the competence to complete meiosis, to be fertilized, and to support embryonic development. This meiotic and developmental competence is gradually established during the course of oocyte and follicle development, and is determined in large part by the autonomous gene expression program intrinsic to the oocyte. In order to explore the regulatory role of LSM14B in oocyte, we analyzed the effect of Lsm14b KO on gene expression in GV-stage fully-grown oocytes (FGOs) in mice by comparing the corresponding transcriptomes via RNA-Seq Analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE204773 | GEO | 2023/09/08

REPOSITORIES: GEO

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