Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Comparative genomics of ten clinical Candida albicans strains

ABSTRACT: Candida albicans is the most common fungal pathogen in humans. C.albicans tolerates aneuploidy of all of its chromosomes. Genome plasticity is a hallmark of C.albicans. It is an adaptation strategy of this species. But questions like the extent of such genomic variability, which genes contribute to the divergence, and what mechanisms drive the adaptive genetic change, are not well answered yet.

ORGANISM(S): Candida albicans

PROVIDER: GSE20509 | GEO | 2011/10/01

SECONDARY ACCESSION(S): PRJNA125225

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Comparative genomics of ten clinical Candida albicans strains

Project description:Candida albicans is the most common fungal pathogen in humans. C.albicans tolerates aneuploidy of all of its chromosomes. Genome plasticity is a hallmark of C.albicans. It is an adaptation strategy of this species. But questions like the extent of such genomic variability, which genes contribute to the divergence, and what mechanisms drive the adaptive genetic change, are not well answered yet. We used array-based comparative genomic hybridization (array CGH) to investigate the diversity of gene contents of 10 clinical C.albicans strains, of various anatomical origins and genotypes. One self to self hybridization was included as a control.

2011-09-30 | E-GEOD-20509 | biostudies-arrayexpress

Comparative genomics of clinical Candida albicans strains

2010-11-05 | GSE18819 | GEO

Early RNA sequencing of human monocytes in presence of Candida albicans

Project description:C.albicans induces the upregulation of inflammation related genes at the same time it also induces TGF-ß signalling pathway related genes from human blood derived monocytes. RNA sequencing was prerformed from Candida albicans co-incubated monoyctes from 3 different donors. Candida albicans significantly upregulates 6363 genes in human blood derived monocytes in 1h of co-incubation.

2019-10-11 | GSE138681 | GEO

Transcriptome dynamics during interaction of NK cells and Candida albicans

Project description:NK cells are part of the innate immune system and therefore directly involved in the response to a Candida albicans infection. Our aim is to better understand the interaction of NK cells and C.albicans cells. Natural Killer cells (NK cells) were isolated from blood of 3 different donors and coincubated with Candida albicans. Transcriptome analysis was performed after 3 and 6 hours using an Illumina HumanHT-12 v4 Expression BeadChip.

2016-06-01 | E-MTAB-4105 | biostudies-arrayexpress

CGH analysis of Candida albicans strains

Project description:Aneuploidy and the evolution of aneuploid karyotypes of Candida albicans strains was identified using aCGH. Whole chromosome and segmental aneuploidies, (specifically on the left arm of chromosome 5 - shown to be due to isochromosome formation) are associated with the appearance of resistance to the antifungal drug fluconazole. Keywords: Comparative Genomic Hybridization

2006-06-30 | GSE4995 | GEO

Comparative genomics of a fluconazole-resistant Candida albicans strain CaLY350.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH).

2014-06-24 | GSE48531 | GEO

Comparative genomics of the srd1 null mutant Candida albicans strain CaLY202.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH).

2014-06-24 | GSE48530 | GEO

Comparative genomics of a fluconazole-resistant variant Candida albicans strain CaLY188.

Project description:To investigate the diversity of gene contents of Candida albicans strain by array-based comparative genomic hybridization (array CGH; aCGH).

2014-06-24 | GSE48529 | GEO

Antifungal effect of Sesamol (Ses) on C. albicans SC5314

Project description:Transcriptional profiling of Candida cells comparing the control vs Ses treated cells Organism : Candida albicans, Agilent custom C.albicans Gene Expression 8x15k Array (AMADID: 026377) designed by Genotypic Technology Private Limited

2016-07-18 | E-GEOD-83080 | biostudies-arrayexpress

Candida albicans

Project description:Candida albicans

| PRJNA308106 | ENA