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Hepatocyte nuclear factor 1β binding in E14.5 kidney

ABSTRACT: HNF-1β mutations are one of the most common single-gene mutations that underlie kidney developmental disease. Hepatocyte nuclear factor 1β (HNF-1β) is essential for kidney development, but its functions in kidney development are incompletely understood. We identified 8284 HNF-1β binding sites using ChIP-sequencing. The majority of these peaks map to promoter (26%), intron (34%) or distal intergenic regions (37.4%) of the mouse genome. 61% of peaks map to protein coding genes, 12% map to long-noncoding RNAs, and 2% map to miRNAs.

ORGANISM(S): Mus musculus

PROVIDER: GSE205189 | GEO | 2022/10/20

REPOSITORIES: GEO

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Hepatocyte nuclear factor 1β binding in E14.5 kidney

Project description:Hepatocyte nuclear factor 1β binding in E14.5 kidney

| PRJNA844065 | ENA

Mus musculus

Project description:Hnf-1β ChIP-Seq

| PRJNA290705 | ENA

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