Transcriptomics

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Buffered hypercapnia alters the transcriptional profile in monocytes.


ABSTRACT: In monocytes we used RNA-sequencing to investigate the effect of 4hrs of exposure to buffered hypercapnia (10% CO2) compared to normocapnia (5% CO2) with and without the pro-inflammatory stimulus LPS (2.5ug/ml) for the final 2hrs. Buffered hypercapnia causes transcriptional changes associated with altered metabolic function in both the basal and stimulated states.

ORGANISM(S): Homo sapiens

PROVIDER: GSE206333 | GEO | 2023/04/07

REPOSITORIES: GEO

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