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METTL3-dependent m6A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling

ABSTRACT: To investigate the effect of Mettl3 in the uterus, we generated mice with conditional ablation of Mettl3 in progesterone receptor (PR)–positive cells (PgrCre Mettl3 fl/fl). And the uterus of Mettl3 cKO and control mice on GD4 were obtained for RNA-seq analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE208096 | GEO | 2023/09/07

REPOSITORIES: GEO

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METTL3-dependent m6A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling

Project description:METTL3-dependent m6A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling

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