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Transcriptomic analysis of AGS treatment in human mesothelioma

ABSTRACT: We analysed the molecular effects on gene modulation exerted by aglianico grape seed extract (AGS) in mesothelioma. Previous results allowed to demonstrate that AGS polar extracts determined apoptosis in three different mesothelioma cell lines including one resistant to conventional chemotherapeutic treatment. In addition this treatment affected tumorigenic and invasive properties of these cells We used microarrays to identify molecular pathway deregulated by AGS treatment and involved in apoptosis induction.

ORGANISM(S): Homo sapiens

PROVIDER: GSE208183 | GEO | 2023/01/25

REPOSITORIES: GEO

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