Transcriptomics

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Transcriptional profiling of Gastrocnemius Muscle in Pompe's disease


ABSTRACT: Study identifying transcriptional differences present between C57BL/6J and B6;129-Gaatm1Rabn/J mice, or driven by Enzyme Replacement Therapy (ERT), Substrate Reduction Therapy (SRT), or Both, administered to the mutant strain. All expression profiles were assessed in bulk gastrocnemius muscle collected from 18-21 week-old mice that had been provided with chow formulated with vehicle (veh.), MZ-101 (SRT), or alglucosidase alfa 20mg/kg biweekly (ERT) for 12 weeks.

ORGANISM(S): Mus musculus

PROVIDER: GSE208215 | GEO | 2024/01/01

REPOSITORIES: GEO

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