Transcriptomics

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Analaysis of global effect of the glucocorticoid fluocinolone acetonide on gene expression in human REDD1 KO HaCaT keratinocytes in comparison to Cas9 HaCaT cells


ABSTRACT: REDD1 is required for full amplitude activation of the glucocorticoid receptor. In keratinocytes lacking REDD1 both gene activation and repression by glucocorticoid fluocinolone acetonide was significantly blunted.

ORGANISM(S): Homo sapiens

PROVIDER: GSE209519 | GEO | 2022/07/23

REPOSITORIES: GEO

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