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Effect of endothelial ADAM10 deficiency on the aorta in an atherosclerosis mouse model

ABSTRACT: Mice lacking ADAM10 in endothelial cells (Tie2Cre driven) and flox-control mice were injected with an AAV8-PCSK9 virus and put on a Western-type diet for 10 weeks to induce atherosclerosis. Aorta's (Thoracoabdominal) were isolated (removal of PVAT) and processed for RNA-sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE209602 | GEO | 2023/02/24

REPOSITORIES: GEO

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