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Localized condensation of the cBAF remodeler is governed by ARID1A/B and is required for transcriptional activation [CUT&Tag]

ABSTRACT: This study investigates the role of the ARID1A/B subunits of the cBAF complex using in vitro and cell-based models. Specifically, we find that the N-terminal disordered region of ARID1A/B and the DNA binding ARID domain are required for condensation and proper orientation on chromatin respectively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE209955 | GEO | 2023/10/01

REPOSITORIES: GEO

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