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A ribosomal protein homolog modulates gene expression and virulence in a bacterial pathogen

ABSTRACT: To assess which F. tularensis LVS transcripts are impacted by loss of bS21-2, we generated cells lacking the gene encoding bS21-2 (LVS ∆rpsU2). We then grew wild-type cells containing an empty vector (LVS pF), cells lacking bS21-2 with empty vector (LVS ∆rpsU2 pF), and cells lacking the native bS21-2 but ectopically expressing bS21-2 from a plasmid (LVS ∆rpsU2 pF-rpsU2-V). We isolated RNA from mid-log phase cells and analyzed by RNA-Seq.

ORGANISM(S): Francisella tularensis subsp. holarctica LVS

PROVIDER: GSE210766 | GEO | 2022/09/09

REPOSITORIES: GEO

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