Genomics

Dataset Information

0

Transcriptional profiling of striatum in METH self-administered rats [miRNA]


ABSTRACT: This study aimed to identify changes in novel miRNAs and their target genes during METH self-administration and investigate their roles in METH-induced locomotion. RNA sequencing analysis revealed that mir-183-5p was upregulated in the striatum of METH self-administered rats, and target gene prediction revealed that the glucocorticoid receptor (GR) gene, Nr3c1, was a potential target gene for mir-183-5p. We confirmed that single and repeated METH administrations increased METH-induced locomotion and plasma corticosterone levels in rats.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE211185 | GEO | 2022/10/19

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-10-19 | GSE211184 | GEO
2022-05-26 | PXD026763 | Pride
2024-09-25 | GSE220896 | GEO
2007-01-04 | E-MEXP-948 | biostudies-arrayexpress
2021-09-08 | PXD013987 | Pride
2016-06-01 | PXD003596 | Pride
2023-02-01 | GSE203268 | GEO
| PRJEB33332 | ENA
2015-09-23 | E-GEOD-71950 | biostudies-arrayexpress
2017-08-24 | GSE102969 | GEO