Transcriptomics

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Epigenetic Control over IFN Type-I Response antagonizes self-renewal in acute myeloid leukemia (RNA-seq)


ABSTRACT: To investigate the impact of PHF8 demethylase activity and PHF8 phosphorylation changes in blocking AML cells progression. We established THP1-wt, THP1-PHF8 and THP1-F279S cell lines for demethylase activity studies and THP1-PHF8AA and THP1-PHF8DD for phosphorylation studies.

ORGANISM(S): Homo sapiens

PROVIDER: GSE211642 | GEO | 2024/03/11

REPOSITORIES: GEO

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