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Selective Translation of Maternal mRNA by eIF4E1B Controls Oocyte to Embryo Transition

ABSTRACT: To identify mRNAs loaded onto eIF4E1B and eIF4E, LACE-seq was performed using eIF4E1B and eIF4E immunoprecipitated mRNAs from mouse fully grown oocytes RNA co-precipitated with eIF4E1B and eIF4E differed from the control RNA enriched by the control IgG rabbit serum antibody.

ORGANISM(S): Mus musculus

PROVIDER: GSE213866 | GEO | 2023/02/21

REPOSITORIES: GEO

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eIF4E1b is a non-canonical eIF4E required for maternal mRNA dormancy

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