Transcriptomics

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Expression data from Myotonic dystrophy type 1 (DM1) patient-derived induced pluripotent cell


ABSTRACT: DM1-iPSCs were generated from the peripheral blood of male adult patients. All clones were generated using episomal vectors. For skeletal muscle differentiation of the DM1-iPSCs, tet-on MYOD1 expression vector was transfected into DM1-iPSCs. To examine whether DM1-iPSC clones with different repeat sizes have acquired different characteristics, we isolated DM1-iPSC clones with different repeat sizes. We isolated 2 clones (S45 and S118) showing repeat size of 400~900, 2 clones (S14 and S24) showing repeat size of 1200~1600, and 2 clones (S1 and S16) showing repeat size of 1800~2800.

ORGANISM(S): Homo sapiens

PROVIDER: GSE214626 | GEO | 2024/12/16

REPOSITORIES: GEO

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