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Gene expression of antigen presenting cells in tumor and spleen of mice receiving either a self-assembling nanoparticle vaccine or an adenovirus vaccination by different routes.

ABSTRACT: Intravenous vaccination with different vaccines modulates the cells in the tumor microenvironemt. We sought to characterize the effects of vaccination by different routes at single cell resolution to determine what key changes are associated with the improved efficacy we observe when vaccines are given systemically as opposed to locally.

ORGANISM(S): Mus musculus

PROVIDER: GSE214741 | GEO | 2022/10/07

REPOSITORIES: GEO

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Blood transcriptome following BCG vaccination administered via different routes in rhesus macaques

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A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S)

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Genome-wide profiling of whole blood from healthy adult volunteers before and after receiving non-live vaccines including seasonal influenza or pneumococcal vaccine or placebo (saline) injections I

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