Pseudogenes limit the identification of novel common transcripts generated by their parent genes
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ABSTRACT: Genomic sequences with high sequence similarity, such as parent-pseudogene pairs, cause short sequencing reads to align to multiple locations, thus complicating genomic analyses. However, their impact on transcriptomic analyses, including the estimation of gene expression and transcript annotation, has been less studied. Here, we investigated the impact of pseudogenes on transcriptomic analyses.
ORGANISM(S): Homo sapiens
PROVIDER: GSE215459 | GEO | 2022/10/15
REPOSITORIES: GEO
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