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GsMTx4 suppresses pro-inflammatory gene expression in DSS-induced colitis in mice.

ABSTRACT: The spider venom-derived peptide GsMTx4 specifically inhibits mechanosensory ion channels. It has been reported that GsMTx4 plays an immunoregulatory role in several inflammatory conditions. Therefore, we administrated GsMTx4 to mice with dextran sodium sulfate (DSS)-induced acute colitis, to explore whether it regulates inflammatory responses in colitis.

ORGANISM(S): Mus musculus

PROVIDER: GSE215772 | GEO | 2023/10/15

REPOSITORIES: GEO

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