Transcriptomics

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Role of steroidogenic factor 1 in the regulation of the ovarian reserve


ABSTRACT: The ovarian reserve of follicles comprises all oocytes for lifetime fertility and once formed, it is non renewing. The orphan nuclear receptor steroidogenic factor 1 (SF-1; Nr5a1) is essential for steroidogenesis, but its role in the earliest stages of follicular development is not known. We therefore developed a model of conditional depletion of SF-1 from prenatal ovaries and performed RNAsequencing to identify SF-1 regulated genes.

ORGANISM(S): Mus musculus

PROVIDER: GSE216420 | GEO | 2023/07/10

REPOSITORIES: GEO

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