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RNA Methyltransferase METTL16's Protein Domains Have Differential Functional Effects on Cell Processes

ABSTRACT: To investigate the cellular role of METTL16, we established HEK293 cell lines over expressing wild-type METTL16 or METTL16 methylation and RNA binding mutations. We then removed endogenous METTL16 from the cells using CRISPR. We then performed gene expression profiling analysis using data obtained from RNA-seq of the various cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE217192 | GEO | 2023/06/29

REPOSITORIES: GEO

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RNA Methyltransferase METTL16’s Protein Domains Have Differential Functional Effects on Cell Processes

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RNA Methyltransferase METTL16's Protein Domains Have Differential Functional Effects on Cell Processes.

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