Transcriptomics

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The Chd4 helicase regulates chromatin accessibility and gene expression critical for β-cell function in vivo [RNA-seq]


ABSTRACT: To establish the role of Chd4 on controlling gene expression programs in the beta cell, we generated a tamoxifen-inducible, beta-cell-specific knockout mouse model; control (MIP-CreERT; Chd4flox/+;R26RtdTomato) and Chd4Db (MIP-CreERT; Chd4flox/flox;R26RtdTomato.

ORGANISM(S): Mus musculus

PROVIDER: GSE217445 | GEO | 2023/05/31

REPOSITORIES: GEO

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