Transcriptomics

Dataset Information

0

Hair follicles modulate skin barrier function


ABSTRACT: We generated KA mutant mice (Krt14-CreERT + ABCA12-flox/flox) and controls (ABCA12-flox/flox) that enabled us to assess the effects of deleting a critical barrier gene, ABCA12, in the skin epidermis following tamoxifen treatment. These studies identified numerous differentially expressed genes (DEGs) upon barrier disruption/ABCA12 deletion, including compensatory upregulation of genes involved with epidermal differentiation and barrier function. Overall, this data-set provides a global view of molecular changes that occur in adult mouse skin following barrier perturbation.

ORGANISM(S): Mus musculus

PROVIDER: GSE254889 | GEO | 2024/05/20

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2012-06-20 | E-GEOD-38830 | biostudies-arrayexpress
2023-05-31 | GSE217445 | GEO
2023-05-31 | GSE217444 | GEO
2020-09-02 | GSE131903 | GEO
2008-06-20 | E-GEOD-10726 | biostudies-arrayexpress
2014-04-18 | E-GEOD-35093 | biostudies-arrayexpress
2014-04-18 | GSE35093 | GEO
2012-05-01 | GSE37655 | GEO
2012-04-30 | E-GEOD-37655 | biostudies-arrayexpress
2020-06-03 | GSE115299 | GEO