Transcriptomics

Dataset Information

0

Expression data from Caenorhabditis elegans exposed to albendazole


ABSTRACT: We have investigated how the model nematode Caenorhabditis elegans responds to and metabolizes albendazole; an important anthelmintic for human and animal parasite control. The transcriptional response of the mutant strain CB3474 ben-1(e1880)III, which is highly resistant to benzimidazoles due to a null mutation in the β-tubulin drug target, was examined. This approach was successful in minimizing transcriptional responses associated with non-specific stress or with the drug mode of action, resulting in only in a small subset of genes showing differential expression in response to drug exposure.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE21747 | GEO | 2010/06/14

SECONDARY ACCESSION(S): PRJNA127333

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2010-06-23 | E-GEOD-21747 | biostudies-arrayexpress
2019-04-30 | GSE130466 | GEO
2021-03-09 | GSE101784 | GEO
2024-04-22 | PXD048945 | Pride
2024-01-29 | PXD042930 | Pride
2021-02-05 | GSE163419 | GEO
2014-06-03 | E-GEOD-58136 | biostudies-arrayexpress
2014-06-03 | GSE58136 | GEO
2024-06-05 | GSE226329 | GEO
2011-04-01 | GSE22660 | GEO