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MiR146a-loaded engineered exosomes released from silk fibroin patch promote diabetic wound healing

ABSTRACT: Unhealable diabetic wounds need to be addressed with the help of newer, more efficacious strategies. Exosomes combined with biomaterials for sustained delivery of therapeutic agents are expected to bring new hope for chronic wound treatment. Here, the engineered exosomes modified for efficiently loading miR-146a and attaching to silk fibroin patch were demonstrated to promote diabetic wound healing. The transcriptomics analysis suggested anti-inflammatory and regenerative effects with SGM-miR146a-Exo@SFP treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE217981 | GEO | 2022/11/19

REPOSITORIES: GEO

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MiR146a-loaded engineered exosomes released from silk fibroin patch promote diabetic wound healing

Project description:MiR146a-loaded engineered exosomes released from silk fibroin patch promote diabetic wound healing

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Expression data from silkworm posterior silk glands at the late larval stages

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Expression data from silkworm posterior silk glands at the late larval stages

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Bombyx mori anterior silk gland LC-MS/MS

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Residue information of degraded silk relics

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2023-05-12 | GSE203028 | GEO

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Transcript profile analyses of maize silk strands during silk senescence

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2022-08-16 | E-MTAB-10847 | biostudies-arrayexpress

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