Screening for altered plasma miRNAs in traumatic brain injured patients
Ontology highlight
ABSTRACT: In this study, we examined if the composition of plasma miRNAs is altered in patients with traumatic brain injury (TBI), and if these changes can be used as diagnostic markers. A microarray containing 875 human miRNAs was used to compare the miRNA profile of plasma collected from severe TBI patients (GCS ≤ 8) to that of age-, gender-, and race-matched healthy volunteers. This screen identified 108 miRNAs in the plasma of healthy volunteers. Of these, 52 were found to be altered in plasma samples from persons with severe TBI, and an additional 8 miRNAs were detected only in the plasma of TBI patients.
ORGANISM(S): Homo sapiens
PROVIDER: GSE21854 | GEO | 2011/04/06
SECONDARY ACCESSION(S): PRJNA127071
REPOSITORIES: GEO
ACCESS DATA