Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA Seq off visceral adipose tissue from human Cushing patients and Controls

ABSTRACT: Visceral adipose tissue from human patients with Cushing was sequnced to identify novel markers of disease progression and other changes related to the disease in adipose tissue.

ORGANISM(S): Homo sapiens

PROVIDER: GSE218965 | GEO | 2023/08/30

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA Seq off visceral adipose tissue from human Cushing patients and Controls

Project description:RNA Seq off visceral adipose tissue from human Cushing patients and Controls

| PRJNA906468 | ENA

Transcriptomic and epigenetic analysis of adipose tissue in Cushing Syndrome [mouse]

Project description:Chronic glucocorticoids (GCs) exposure, resulting from endogenous Cushing Syndrome (CS) or prescribed GCs therapy, is associated with a high cardiometabolic burden. Moreover, previous studies have reported persistence of metabolic syndrome features after remission of hypercortisolism and in particular in visceral adipose tissue (VAT). Thus, in this study we want to analyze the transcriptomic alterations in VAT during active and cured CS and correlate these persistent gene expression changes with histone modifications induced by GCs.

2021-09-03 | GSE153934 | GEO

Transcriptomic and epigenetic analysis of adipose tissue in Cushing Syndrome [human]

2021-09-03 | GSE140126 | GEO

Visceral adipose tissue macrophage subsets

Project description:Visceral adipose tissue macrophage subsets

| PRJNA484897 | ENA

The Hidden Culprit of Visceral Fat: Dysfunctional Subcutaneous Adipose Tissue – Adipose tissue proteomics

Project description:To investigate the proteomic profiles of paired subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) samples, as well as their correlations with clinical traits in severely obese patients, and to identify potential serum protein markers associated with tissue expression or metabolic states.

2023-10-16 | PXD041721 | Pride

Epigenome analysis of the human visceral adipose tissue

Project description:Visceral adipose tissue samples were obtained from severely obese individuals that underwent bariatric surgery. The goal of this study was to identify tissue specific methylation QTLs. Whole-transcriptome subcutaneous adipose tissue methylation levels were determined in 71 individuals with a BMI >35 kg/m2. Bisulphite converted DNA from the 71 visceral adipose tissue samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip.

2014-09-17 | E-GEOD-61453 | biostudies-arrayexpress

SO018 visceral adipose tissue gene expression

Project description:SO018 visceral adipose tissue gene expression

| PRJNA735944 | ENA

The human diabetes-specific visceral adipose tissue proteome: insights into mechanisms of adipose tissue dysfunction in metabolic disease

Project description:Introduction: The human adipose tissue proteome associated with type 2 diabetes (DM) is not well described. An understanding of the DM-specific adipose tissue proteome would provide insight into mechanisms underlying the pathogenesis of DM. Methods: We used label-free proteomics analysis to quantify differences between visceral adipose tissue samples from obese women with and without DM. Results: 2640 protein groups were identified and 1965 were subject to statistical analysis. 23 were differently abundant between groups (q < 0.1, moderated t-test, n = 10). Proteins localized to the mitochondria or involved in mitochondrial functions including the TCA cycle and fatty acid metabolism were decreased in abundance in samples from women with DM relative to NDM samples while proteins involved in cytoskeletal function and innate inflammatory signaling pathways were increased. Conclusion: The visceral adipose tissue proteome in DM is characterized by defects in mitochondrial function, TCA metabolism, inflammation and immunity, and cytoskeletal function. Alterations in the levels of specific proteins associated with these pathways provide insight into mechanisms of adipose tissue dysfunction in the context of metabolic disease.

2020-03-27 | MSV000085169 | MassIVE

Transcriptome-wide maps of subcutaneous adipose tissues and visceral adipose tissues in cancer-associated cachexia patients

Project description:In order to identify differentially expressed RNAs among subcutaneous and visceral adipose tissue of cachxtic patients, we recruited three colon cancer patients with remarkable weight lose. We harvested adipose tissue from abdomen of patients at time of surgery and completed transcriptome sequencing using Illumina platform.

2021-10-26 | GSE186466 | GEO

Subcutaneous adipose tissue and visceral adipose tissue gene expression profiles in Mexican patients with obesity

Project description:Using RNA isolated from subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) samples obtained from control and class I, II and III obese patients undergoing inguinal hernia repair and laparoscopic cholecystectomy, we compared the gene expression profiles between SAT and VAT using microarrays and validated the findings by real-time quantitative PCR.

2016-07-20 | GSE84599 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data