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Single cell gene expression from WT and Il2ra-deficient P14 Murine CD8 T cells in response to LCMV armstrong infection.

ABSTRACT: Il2ra exhibits highly dynamic expression early in CD8 T cell response to LCMV infection, and its' transient high expression in a subset of these cells (termed common effector/memory progenitor or EMP) suggested it may promote multilineage potential. Here we interrogated the functional role of Il2ra through the inference of single-cell trajectories in wildtype and Ilra-deficient P14 CD8 T cells 6 days after LCMV armstrong infections.

ORGANISM(S): Mus musculus

PROVIDER: GSE219266 | GEO | 2024/12/16

REPOSITORIES: GEO

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