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Genomic predictors of response to doxorubicin versus docetaxel in breast cancer

ABSTRACT: Low topo2a expression and ER-negative status were predictors of response to doxorubicin, while small tumor size and ER-negative status predicted response to docetaxel. Docetaxel was superior to doxorubicin in triple-negative/basal-like tumors, while no significant differences between these drugs were seen in the remaining intrinsic subtypes Keywords: reference x sample

ORGANISM(S): Homo sapiens

PROVIDER: GSE21997 | GEO | 2011/05/27

SECONDARY ACCESSION(S): PRJNA127219

REPOSITORIES: GEO

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Genomic predictors of response to doxorubicin versus docetaxel in breast cancer

Project description:Low topo2a expression and ER-negative status were predictors of response to doxorubicin, while small tumor size and ER-negative status predicted response to docetaxel. Docetaxel was superior to doxorubicin in triple-negative/basal-like tumors, while no significant differences between these drugs were seen in the remaining intrinsic subtypes Keywords: reference x sample reference x sample

2011-05-27 | E-GEOD-21997 | biostudies-arrayexpress

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Homo sapiens

Project description:Genomic predictors of response to doxorubicin versus docetaxel in breast cancer

| PRJNA127219 | ENA

Clinical and Pathologic Response of the Primary Tumor in Women Receiving Neoadjuvant Docetaxel-Capecitabine (+/- Trastuzumab) Chemotherapy

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