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Engineering an inhibitor resistant human CSF1R variant for microglia replacement [InVitro_RNA]

ABSTRACT: iPSC-derived microglia expressing the wildtype, G795A, or G795C CSF1R variants were generated in vitro and treated with either DMSO or Plexxicon 5622 in order to compare the gene expression differences exising between genotypes at baseline or following CSF1R inhibtion.

ORGANISM(S): Homo sapiens

PROVIDER: GSE220213 | GEO | 2022/12/21

REPOSITORIES: GEO

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Engineering an inhibitor resistant human CSF1R variant for microglia replacement [InVivo_RNA]

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