Stereopure phosphoryl guanidine backbone chemistry increases the potency and durability of gene silencing by RNA interference
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ABSTRACT: To investigate the potential of "off target" of RNAi knockdown, primary mouse hepatocytes were treated with molecules targeting Ttr. We then performed gene expression profiling analysis using data obtained from RNA-seq of cell at two different doses along with an untreated control.
ORGANISM(S): Mus musculus
PROVIDER: GSE220502 | GEO | 2023/05/25
REPOSITORIES: GEO
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