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Analysis of the role of Dectin-1 in the development of intestinal tumor-infiltrating myeloid cells [scRNA-Seq]

ABSTRACT: To investigate the potential role of Dectin-1 in the development of intestinal tumor-infiltrating myeloid cells, we purified CD11b+ & CD11c+ cells from colorectal polyps of wild-type (WT) or Dectin-1 deficient (Clec7a–/–, KO) mice after azoxymethane (AOM) and 3 cycles of dextran-sodium-sulfate (DSS)-administration for 16 weeks, and compared the differences in the populations of each myeloid cell subset by scRNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE221204 | GEO | 2023/02/21

REPOSITORIES: GEO

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