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CircAkt3 participates in bone cancer pain progression in rats by modulating MAPK signalling pathway

ABSTRACT: CircRNA parent genes were mainly enriched in MAPK and neurodevelopmental signalling pathways. CircAkt3 and circMap4k1 were significantly up-regulated in the bone cancer pain group. CircaAkt3 may increase p-ERK expression by upregulating Col8a1, which may further activate the MAPK pathway.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE224978 | GEO | 2023/02/14

REPOSITORIES: GEO

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