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Role of TET1-mediated epigenetic modulation in Alzheimer’s disease [RNA-Seq]

ABSTRACT: To investigate the influence the partial loss of Tet1 has on AD pathogenesis in 5xFAD mice, we crossed a Tet1 KO mouse line with the 5xFAD mouse line to generate WT, 5xFAD, Tet1(+/-), and FAD/Tet1(+/-) mice. We then performed gene expression profiling analysis using data obtained from RNA-seq from biological replicates of mice comprised of 4 different genotypes.

ORGANISM(S): Mus musculus

PROVIDER: GSE226053 | GEO | 2023/10/03

REPOSITORIES: GEO

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Role of TET1-mediated epigenetic modulation in Alzheimer’s disease [5hmC-Capture]

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