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Effect of knockout of and pathogenic mutations in HNRNPH2 on gene expression in human iPSC-derived neurons

ABSTRACT: To investigate the effect of knockout of and pathogenic mutatations in HNRNPH2, we generated human iPSC lines in which endogenous HNRNPH2 has been knocked out, or 3 pathogenic mutations (R206W, R206Q, and P209L) have been knocked into the endogenous HNRNPH2 using CRISPR Cas-9.

ORGANISM(S): Homo sapiens

PROVIDER: GSE226525 | GEO | 2023/07/19

REPOSITORIES: GEO

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