Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/MAPK pathway [RNA-seq]
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ABSTRACT: To investigate the function of SETD2 in SMAD4-mutant colorectal cancer, we induced colorectal cancer in mice with intestinal epithelium-specific knockout of SMAD4 and SETD2 using AOM/DSS treatment.
ORGANISM(S): Mus musculus
PROVIDER: GSE228024 | GEO | 2023/11/21
REPOSITORIES: GEO
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